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Monday, December 6, 2010

Everyone is ageing at every moment of their lives, it's just that some of us are ahead of the rest”


Do you really want to live forever?

Candles on a cake
Science is striving to reverse the ageing process so we can all live longer, but that does come with its drawbacks, says Joan Bakewell in A Point of View.
Last week scientists at Harvard medical school reversed the ageing process in elderly mice. Please don't get excited, unless you're a mouse that is. The application to humans is a long way off and even if it will one day be possible, there are many issues attendant on a population that has the means to live forever.
Harvard's research will be welcomed by two entirely different groups of people. Instantly, and possibly without too much thought, by those who pander to and encourage the wish of women not to "lose their looks" as they grow older. Nobody loses their looks, they just have different looks.
But by a universally agreed norm, within our culture beauty carries a prize. Ever since Paris offered the apple and Helen launched a thousand ships, we have known that beauty, especially in women, offers an easier life, more attention, more opportunities, friends, lovers, gratification.
I hope you won't argue with me in this - in my own small way I've lived it. I was once thought pretty, now young people give up their seat to me on the Tube. Life brings many changes and growing old involves adapting to them.
Creepy
Women in their 40s and 50s find it hard when the first wrinkles hit. They are a sitting target for a multi-million pound cosmetics and skin care industry that makes glamorous commercials only just this side of legally acceptable, promising to slow the ageing process of the female body. Along come the geriatric mice and their hopes soar. But the promise of eternal youth has deluded more than Dorian Gray. No need to make space just yet for the painting in the attic. The human body ages, get used to it.
Woman have botox Women go to extremes to look younger
The other eyebrows that will be raised by the news from Harvard belong to the scientists around the world who are now engaged on the serious matter of ageing and how it happens. Medical intervention once seemed limited to curing us of diseases that kill. In my childhood, diphtheria and scarlet fever still carried people off, I had friends crippled by polio and aunts deformed by rickets. All this seemed the proper field for medical intervention.
We seemed to accept that the big killers struck people in late middle age - most often, it seemed to me as a child, cancer, which was then an ill-defined umbrella term referred to in hushed whispers as "the big C".
We all know what happened next, a great swathe of advances in hygiene and medicine drove the major killers on to the back foot. From a combination of better lifestyle, cleaner cities and the benefits of a free health service, people began living longer.
We hear regularly of the latest treatments for coronary heart disease, breast cancer, kidney failure, and we live in the belief that when we have an unwelcome diagnosis the full force of medical knowledge will be marshalled for our benefit. We have come to expect better. Now we want life to go on forever.
There are people frantic for eternal life. A few years ago I met people who were vesting their savings in the cryogenic movement - a movement that undertook to freeze your body after you were dead and keep it until such time as science came up with the solution to whatever had killed you, at which moment you could be defrosted, cured, and resume your life.
Dogma
Little attention was being paid to two serious disadvantages: what might the world be like when you emerged from the deep freeze, would they still have iPods and aeroplanes, supermarkets and killer heels. And secondly, why would anyone bother to defrost you when you had already paid up and had no possible means of redress. Who would want to resurrect a cluster of damp and out of date individuals, who would merely hang around adding to the world's population problem?

Joan Bakewell
Incidentally, I understood that some deluded individuals who didn't have enough money for the whole body treatment were told they could have their head alone frozen, and expect it to be stitched onto any available body when the time came. Science fiction can't get much creepier.
While most of us don't want to live forever, many of us would enjoy living longer. At the same time we would like the planet to survive as we know it. There is a contradiction in contemplating a world where everyone lives much longer and where the planet's resources are finite.
Unless we can learn to eat sand we should bear in mind the fates of places like Angkor Wat and Easter Island, places once dense with people and culture now empty ruins. Populations have died out or been massively relocated before now. Again, science fiction lurks in the wings. Flights to Mars anyone?
The fine line we have to travel is one that we are currently mapping out. There are no precedents. We must measure the gains to our ageing population of today's fast-developing medicine against the problems created globally. To even approach this subject is to invite reproach.
When China judged the rapid growth of its population needed control and instituted state policy of a one child family, other cultures threw up their collective hands in horror. This smelled to them of eugenics, of selective breeding, of Hitler's worst fantasies. It is indeed a harsh dogma. When I was there in the 80s it was explained to me that you could break the rule as long as you incurred penalties. If a family had a second child they were downgraded in the claim they had on state housing. And so on, another child and further penalties.
Flesh
I don't know whether this system still operates in today's China, but we have seen its impact more recently when a school collapsed killing some of the pupils. The anguish of parents was as agonising as any others and we could sympathise fully with that. Added to it was the awareness that many had lost their only child.
Removing eggs from cryogenic storage Cryogenics involves deep freezing
But let's stay close to home for in truth there are many dilemmas on our own doorstep. I read this week of a new business launched in October that will for a fee freeze stem cells taken from teeth, fat, bone marrow and other tissues in the belief that such fresh stem cells, once unfrozen, will be of better use than older stem cells in curing ailments that develop later in life.
This is a private commercial venture, but university departments around the country are conducting stem cell research that will help us recover from illnesses that would otherwise kill us. Others are looking into the further possibility of using animal parts for transplants. There is talk of work on Alzheimers, on multiple sclerosis.
Gerontology itself - the study of ageing - is a big growth area. And all this is fine, we are in the right place at the right time, though perhaps some of us are a little late for the anti-ageing bonanza that could be on the way in Britain. I don't worry about that. I have other concerns.
The prospect of more years is of course inviting - living to see the grandchildren marry, watching the tree you planted with such care grow to its full height, seeing our rivers flow clean and full of fish again, all lifestyle pleasures that we would relish.
But there is another prospect and one already known to too many in our communities. It is a life lived in isolation, our earning lives over, our efforts to sustain some life in the mainstream rejected, families far away or indifferent or both.
The occasional and erratic visits from a changing medley of inept carers, food not as we once relished it, but half cooked, half cold, dumped on us by those eager to be gone. The home we know getting shabby, the garden that was once our pride overgrown and run to seed. I wonder what runs through the minds of such people when they read of brave new developments made by scientists in their prime?

Friday, December 3, 2010

Kenya corruption costs government dearly



Demonstrators in Nairobi protest against corruption in politics (Feb 2010) Corruption has long plagued Kenyan politics, causing widespread public anger

Related stories

The Kenyan government has said it could be losing nearly one-third of the national budget to corruption.
Finance ministry officials told a parliamentary committee the losses could be nearly $4bn (£2.5bn) a year.
They said individuals were taking huge sums meant for development projects.
Analysts say many Kenyans will be surprised not by the news of the losses, but by the fact the admission has come from such senior officials.
Kitu kidogo - the Swahili for "something small" - is how the kickbacks are commonly described in Kenya.
Taking 10% of an awarded tender or inflating project costs are said to be the commonest means of dipping into government coffers.
Corruption has been the Achilles heel of successive Kenyan regimes.
But the efforts of the country's newly-appointed anti-corruption commissioner - who now has the power to prosecute individuals - are causing ripples in government quarters.

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Wednesday, December 1, 2010

About Us - Coach Me To Publish™

About Us - Coach Me To Publish

Broke Mexicana stewardesses launch racy calendar


Click to play
The stewardesses paid out of their own pockets to cover production costs
Female flight attendants from ailing Mexican airline Mexicana have launched a racy aviation calendar in an attempt to ease their financial worries.
The 2011 calendar features the 10 women clad in bikinis and sunglasses draped over parts of an aircraft. Its first run sold out before the launch.
The women said they wanted to help themselves after losing so much.
The airline, which has debts of about $800m (£500m), filed for bankruptcy in August and has suspended operations.
The calendar has evoked comparisons with the 1997 film The Full Monty, in which a group of unemployed British steelworkers organise a striptease act.
"It occurred to me because we all needed money, and I thought that with so many pretty girls there were bound to be some who'd be interested," said organiser Coral Perez, quoted by the Associated Press news agency.
Mexicana check-in Mexicana has proposed cutting salaries and staff
The 10 stewardesses each paid some money out of their own pockets towards the 100,000 peso ($8,000) production costs.
A thousand copies of the $12 (£7.50) calendar have already been sold, and a second edition of 3,000 is being produced.
The 89-year-old airline suffered heavy losses because of Mexico's recession in 2009 and an outbreak of swine flu the same year which caused a sharp fall in tourism.
After filing for bankruptcy protection Mexicana proposed deep pay cuts for pilots and crew, as well as a 40% reduction in the workforce.

Experts call for routine HIV testing in high risk areas

Blood tests Routine HIV tests could be carried out in emergency departments

"The later people are diagnosed with HIV, the more difficult and expensive it is to treat them, the poorer their outcome may be, and the more likely they are to have transmitted the infection."
The number of people living with HIV in the UK reached an estimated 86,500 in 2009, but according to the HPA a quarter - almost 21,000 - were unaware of their infection.
The new studies also suggest that doctors may be missing HIV cases because of preconceptions over what someone with the virus may look like.
At present testing is recommended in areas where there are a greater number of cases of HIV but this doesn't happen across the board.
All pregnant women and anyone who is sexually active and attends a clinic for sexually transmitted diseases are automatically offered a test for HIV.
Almost all pregnant women who are offered a test say yes.
And it seems that patients are also fairly relaxed about routine testing for HIV.
The study found that 95% of patients in a casualty ward and nearly 97% in a GP surgery agreed that testing was a good idea.
The Public Health minister Ann Milton was pleased patients had responded positively.
"Earlier diagnosis means people can start treatment as soon as possible and live a near normal life.
"It also helps prevent spreading the virus, so it's good news that people are happy to be tested and we can pick up cases of HIV that could otherwise be missed or found much later."
The proposal wouldn't see routine testing for HIV rolled out everywhere.
Instead it would be focused on areas with the highest rates of HIV.
In England that would cover around a quarter of Primary Care Trusts.

Index finger length prostate cancer clue



Male baby in the womb Babies are exposed to hormones in the womb

Related stories

The length of a man's fingers can provide clues to his risk of prostate cancer, according to new research.
A British Journal of Cancer study found men whose index finger was longer than their ring finger were significantly less likely to develop the disease.
Researchers made the discovery after comparing the hands of 1,500 prostate cancer patients with 3,000 healthy men.
The length of the fingers is fixed before birth and is thought to relate to sex hormone levels in the womb.
Being exposed to less testosterone before birth results in a longer index finger and may protect against prostate cancer later in life, say researchers at the University of Warwick and the Institute of Cancer Research.
One of the report authors, Professor Ros Eeles, said more studies would be needed, but if these confirmed the findings it could be used a simple test for prostate cancer risk.
She said: "This exciting finding means that finger pattern could potentially be used to select at-risk men for ongoing screening, perhaps in combination with other factors such as family history or genetic testing."
The study was funded by the charities Prostate Action and Cancer Research UK.
Emma Halls, chief executive of Prostate Action, said: "This research brings us another step closer to helping determine risk factors for prostate cancer, which is possibly the biggest issue in current thinking about preventing and treating the disease.
"However, we are still a long way from reducing the number of men who die of prostate cancer every year and need more research and education in all areas to achieve this."
Dr Helen Rippon, head of research at The prostate Cancer Charity, said the research added to growing evidence that the balance of hormones we are exposed to before birth influences our health for the rest of our lives.
But she said men with shorter index fingers should not be "unduly worried".
"They share this trait with more than half of all men and it does not mean they will definitely develop prostate cancer in later life."